Anti-GUCA1A Polyclonal Antibody (HA643014)

Name: Anti-GUCA1A Polyclonal Antibody
Brand: abinScience
SKU: HA643014
Price: 96 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

HA643014

Описание

Anti-GUCA1A Polyclonal Antibody (HA643014) is a rabbit polyclonal antibody detecting Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A; GUCA1A; C6orf131; GCAP; GCAP1; GUCA1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human GUCA1A (Met1-Gly201).

Цель

Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A; GUCA1A; C6orf131; GCAP; GCAP1; GUCA1

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P43080, P46065, P43081

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Guanylyl cyclase-activating protein 1 (GUCA1A) is a ~22 kDa protein. Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light.

1. Jiang, L. et al. (2008) Vision research 48, 2425-32. PMID: 18706439

2. Kitiratschky, VB. et al. (2009) Human mutation 30, E782-96. PMID: 19459154

3. Marino, V. et al. (2018) Human molecular genetics 27, 4204-4217. PMID: 30184081

4. Peshenko, IV. et al. (2019) The Journal of biological chemistry 294, 3476-3488. PMID: 30622141

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-GUCA1A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа