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Anti-H1-1 Polyclonal Antibody (HB348014)

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概要
カタログ番号HB348014
説明
Anti-H1-1 Polyclonal Antibody (HB348014) is a rabbit polyclonal antibody detecting Histone H1.1; Histone H1a; H1-1; H1F1; HIST1H1A in ELISA, IHC, WB. Suitable for Human, Bovine, Rat, Mouse, and Chicken.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
種反応性Human, Mouse, Rat
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant human H1-1 (Ala39-Glu118).
ターゲット Histone H1.1; Histone H1a; H1-1; H1F1; HIST1H1A
エンドトキシンレベル Please contact with the lab for this information.
精製 Purified by antigen affinity column.
アクセッション番号 Q02539, G3N131, D4A3K5, P43275, P16402, P43276, P09987, P16403, D3ZBN0, P43277, P10412, P15865, P43274
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Histone H1.1 (H1-1) is a ~21 kDa protein. Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers and promote formation of the H3K27me3 mark by the PRC2/EED-EZH2 complex. Also acts as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

1. Lever, MA. et al. (2000) Nature 408, 873-6. PMID: 11130728
注意事項 For research use only
イメージ
参考文献
Formula
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Formula
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