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| カタログ番号 | HS743014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-HADH Polyclonal Antibody (HS743014) is a rabbit polyclonal antibody detecting HADH in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HADH (Met1-Arg236). | ||||||||
| ターゲット | HCDH, HAD, Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial, HADH, SCHAD, Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase, HAD1, Short-chain 3-hydroxyacyl-CoA dehydrogenase, HADHSC | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q16836 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) is a ~34 kDa protein. Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion. Plays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes. 1. Barycki, JJ. et al. (1999) Biochemistry 38, 5786-98. PMID: 10231530 2. Clayton, PT. et al. (2001) The Journal of clinical investigation 108, 457-65. PMID: 11489939 3. Bennett, MJ. et al. (2006) Molecular genetics and metabolism 89, 74-9. PMID: 16725361 | ||||||||
| 注意事項 | For research use only. |
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