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| カタログ番号 | VK764014 | ||||||||
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| 説明 |
Anti-HAdV-5 Fiber protein/L5 Polyclonal Antibody (VK764014) is a rabbit polyclonal antibody detecting Fiber protein in ELISA, WB.
Highlights
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| 種反応性 | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) | ||||||||
| アプリケーション | ELISA, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant HAdV-5 Fiber protein/L5 (Gly387-Glu581). | ||||||||
| ターゲット | Fiber protein, SPIKE, Protein IV, L5 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P11818 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Fiber protein (L5) is a ~61 kDa protein. Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host coxsackievirus and adenovirus receptor CXADR located at the cell tight junctions to provide virion initial attachment to target cell. The fiber protein binds to CXADR with a higher affinity than CXADR binds to itself, thereby blocking the cell-cell adhesion function of CXADR dimers and leading to local disruption of the tight junction. Fiber protein present on neo-synthesized particles may thus disrupt the junctional integrity in order to facilitate further neighboring cells infection. Fiber proteins are shed during virus entry, when virus is still at the cell surface. | ||||||||
| 注意事項 | For research use only. |
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