Anti-HAdV-7 Shutoff protein/L4 Polyclonal Antibody (VK734014)

Name: Anti-HAdV-7 Shutoff protein/L4 Polyclonal Antibody
Brand: abinScience
SKU: VK734014
Price: 168 USD
Availability: InStock

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100ug

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK734014

Description

Anti-HAdV-7 Shutoff protein/L4 Polyclonal Antibody (VK734014) is a rabbit polyclonal antibody detecting Shutoff protein in ELISA, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Reactivité des espèces

Human adenovirus B serotype 7 (HAdV-7)

Applications

ELISA, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant HAdV-7 Shutoff protein/L4 (Leu373-Arg537).

Cible

Shutoff protein, 100 kDa protein, p100K, 100K-chaperone protein, L4-100K, Shutoff protein 100K, L4

Purification

Purified by antigen affinity column.

Numéro d'accès

Q5EY60

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Shutoff protein (L4) is a ~92 kDa protein. Protein that inhibits host translation while promoting late viral translation by ribosome shunting. Blocks host cap-dependent translation by binding to eIF4G, displacing MKNK1 from cap initiation complexes and preventing EIF4E phosphorylation. Binds to the tripartite leader sequence of viral late mRNAs and recruits host eIF4G, PABPC1/poly-A binding protein and 40S ribosomes subunits on viral mRNAs, allowing ribosome shunting and efficient translation of late viral mRNAs even though conventional translation via ribosome scanning from the cap has been shut off in the host cell. During assembly, acts as a chaperone protein that helps hexon proteins assembly into trimers.

Note

For research use only.

Images

Reférences

Fiche technique

Anti-HAdV-7 Shutoff protein/L4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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