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| カタログ番号 | RD448014 | ||||||||
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| 説明 |
Anti-HAO1 Polyclonal Antibody (RD448014) is a rabbit polyclonal antibody detecting HAO1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Rat HAO1 (Asp61-Ile370). | ||||||||
| ターゲット | 2-Hydroxyacid oxidase 1, EC:1.1.3.15, EC:1.2.3.5, GO, GOX, GOX1, Glycolate oxidase, Glyoxylate oxidase, HAO1, HAOX1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | B0BNF9 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | B0BNF9 | ||||||||
| 背景 | 2-Hydroxyacid oxidase 1 (HAO1) is a ~40 kDa protein. Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate. The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones. Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate. Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2. | ||||||||
| 注意事項 | For research use only |
Western blot analysis was performed using anti-HAO1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat liver lysate
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