

| Número de catálogo | HV192014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human HAS2 (Glu67-Thr172). | ||||||||
| Objetivo | HA synthase 2, Hyaluronan synthase 2, Hyaluronic acid synthase 2, HAS2, Hyaluronate synthase 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q92819 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Hyaluronan synthase 2 (HAS2) is a ~63 kDa protein. Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer (Probable). Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan. 1. Karousou, E. et al. (2010) The Journal of biological chemistry 285, 23647-54. PMID: 20507985 2. Vigetti, D. et al. (2011) The Journal of biological chemistry 286, 7917-7924. PMID: 21228273 3. Rilla, K. et al. (2013) The Journal of biological chemistry 288, 5973-83. PMID: 23303191 4. Kasai, K. et al. (2020) Biochemical and biophysical research communications 533, 732-738. PMID: 32993960 5. Watanabe, K. et al. (1996) The Journal of biological chemistry 271, 22945-8. PMID: 8798477 | ||||||||
| Nota | For research use only. |
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