

| カタログ番号 | HV192014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HAS2 (Glu67-Thr172). | ||||||||
| ターゲット | HA synthase 2, Hyaluronan synthase 2, Hyaluronic acid synthase 2, HAS2, Hyaluronate synthase 2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q92819 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Hyaluronan synthase 2 (HAS2) is a ~63 kDa protein. Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer (Probable). Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan. 1. Karousou, E. et al. (2010) The Journal of biological chemistry 285, 23647-54. PMID: 20507985 2. Vigetti, D. et al. (2011) The Journal of biological chemistry 286, 7917-7924. PMID: 21228273 3. Rilla, K. et al. (2013) The Journal of biological chemistry 288, 5973-83. PMID: 23303191 4. Kasai, K. et al. (2020) Biochemical and biophysical research communications 533, 732-738. PMID: 32993960 5. Watanabe, K. et al. (1996) The Journal of biological chemistry 271, 22945-8. PMID: 8798477 | ||||||||
| 注意事項 | For research use only. |
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