Anti-HCMV/HHV5 HHRF3/US28 Recombinant Nanobody (SAA1107) (VK595033)

Name: Anti-HCMV/HHV5 HHRF3/US28 Recombinant Nanobody (SAA1107)
Brand: abinScience
SKU: VK595033
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK595033

Descripción

Anti-HCMV/HHV5 HHRF3/US28 Nanobody (SAA1107) [SAA1107] (VK595033) is a alpaca monoclonal antibody detecting HHRF3 in ELISA.

Reactividad de especies

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)

Aplicaciones

ELISA

Especie huésped

Alpaca

Clonalidad

Monoclonal

Isotipo

VHH-8His-Cys-tag

ID de clon

SAA1107

Objetivo

G-protein coupled receptor homolog US28, HHRF3, US28

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by Nickel column.

Número de acceso

P69332

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

G-protein coupled receptor homolog US28 (HHRF3) is a ~41 kDa protein. Viral chemokine receptor that plays a critical role in viral pathogenesis, mediating several processes such as cellular migration, differentiation, transformation, and viral latency and reactivation. Binds to a great number of different CC-chemokines including CCL5/RANTES, CCL2/MCP-1, CCL3/MIP-1-alpha as well as CX3CL1/Fractalkine. Transduces signals resulting in the activation of MAP kinase signaling pathways and augmentation of intracellular calcium ion levels, leading to alterations in chemotactic behavior of vascular smooth muscle cells and macrophages. The US28 receptor also exhibits high levels of agonist-independent signaling activity and agonist-independent endocytosis. Interacts with the host Gi complex without activating it, thereby probably interfering with the chemokine-Gi signaling.

1. Burg, JS. et al. (2015) Science (New York, N.Y.) 347, 1113-7. PMID: 25745166

2. Kuhn, DE. et al. (1995) Biochemical and biophysical research communications 211, 325-30. PMID: 7540006

3. Gao, JL. et al. (1994) The Journal of biological chemistry 269, 28539-42. PMID: 7961796

4. Casarosa, P. et al. (2001) The Journal of biological chemistry 276, 1133-7. PMID: 11050102

5. Tsutsumi, N. et al. (2022) Science advances 8, eabl5442. PMID: 35061538

6. Maassen, F. et al. (2025) eLife 14. PMID: 40608405

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-HCMV/HHV5 HHRF3/US28 Nanobody (SAA1107)

Referencias

Datasheet

Anti-HCMV/HHV5 HHRF3/US28 Recombinant Nanobody (SAA1107).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo