

| Numéro de catalogue | VK457014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-HCoV-OC43 NP/Nucleoprotein Polyclonal Antibody (VK457014) is a rabbit polyclonal antibody detecting Nucleoprotein in ELISA, IHC, WB. Suitable for Bovine coronavirus and Equine coronavirus.
Highlights
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| Reactivité des espèces | Human coronavirus OC43 (HCoV-OC43) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant HCoV-OC43 NP/Nucleoprotein (Met1-Ile448). | ||||||||
| Cible | N, NC, Nucleocapsid protein, Nucleoprotein, Protein N | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P33469 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Nucleoprotein (NP) is a ~49 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions. 1. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661 | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-NCAP-CVHOC polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant HCoV-OC43 NP/Nucleoprotein (Catalog No: VK457012)
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