Anti-HCV Protease NS2 Polyclonal Antibody (VK506044)

Name: Anti-HCV Protease NS2 Polyclonal Antibody
Brand: abinScience
SKU: VK506044
Price: 168 USD
Availability: InStock

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50ug
100ug

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SDS

Aperçu

Numéro de catalogue

VK506044

Description

Anti-HCV Protease NS2 Polyclonal Antibody (VK506044) is a rabbit polyclonal antibody detecting Protease NS2. Suitable for Hepatitis C virus genotype 3a.

Reactivité des espèces

Hepatitis C Virus (HCV)

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant HCV Protease NS2 (Leu902-Glu1026).

Cible

Capsid protein C, Core protein precursor, EC:2.7.7.48, EC:3.4.21.98, EC:3.4.22.-, EC:3.6.1.15, EC:3.6.4.13, Envelope glycoprotein E1, Envelope glycoprotein E2, Genome polyprotein, Hepacivirin, Mature core protein, NS1, NS2, NS3 helicase, NS3 protease, NS3P, NS4A, NS4B, NS5A, NS5B, Non-structural protein 2, Non-structural protein 4A, Non-structural protein 4B, Non-structural protein 5A, Protease NS2, RNA-directed RNA polymerase, Serine protease/helicase NS3, Viroporin p7, Viroporin p70, gp32, gp35, gp68, gp70, p21, p23, p27, p56/58, p68, p8

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q81258

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Genome polyprotein (Protease NS2) is a ~329 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable).

1. Jackel-Cram, C. et al. (2007) Journal of hepatology 46, 999-1008. PMID: 17188392

Note

For research use only

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