Anti-HDAC8 Polyclonal Antibody (HV385014)

Name: Anti-HDAC8 Polyclonal Antibody
Brand: abinScience
SKU: HV385014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HV385014

説明

Anti-HDAC8 Polyclonal Antibody (HV385014) is a rabbit polyclonal antibody detecting HDAC8 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human HDAC8 (Met1-Val377).

ターゲット

HDAC8, Histone deacetylase 8, HD8, HDACL1

精製

Purified by antigen affinity column.

アクセッション番号

Q9BY41

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Histone deacetylase 8 (HDAC8) is a ~41 kDa protein. Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

1. Hu, E. et al. (2000) The Journal of biological chemistry 275, 15254-64. PMID: 10748112

2. Van den Wyngaert, I. et al. (2000) FEBS letters 478, 77-83. PMID: 10922473

3. Buggy, JJ. et al. (2000) The Biochemical journal 350 Pt 1, 199-205. PMID: 10926844

4. Lee, H. et al. (2004) Molecular and cellular biology 24, 765-73. PMID: 14701748

5. Wei, W. et al. (2017) Cell research 27, 898-915. PMID: 28497810

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-HDAC8 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-HDAC8 Polyclonal Antibody (HV385014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ