Anti-HEPH Polyclonal Antibody (HV304014)

Name: Anti-HEPH Polyclonal Antibody
Brand: abinScience
SKU: HV304014
Price: 168 USD
Availability: InStock

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Reférences
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SDS

Aperçu

Numéro de catalogue

HV304014

Description

Anti-HEPH Polyclonal Antibody (HV304014) is a rabbit polyclonal antibody detecting HEPH in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human HEPH (Ala24-Cys366).

Cible

HEPH, KIAA0698, Hephaestin

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9BQS7

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Hephaestin is a ~130 kDa protein. Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. By helping iron transfer from cells to blood mainly contributes to dietary iron absorption by the intestinal epithelium and more generally regulates iron levels in the body.

1. Vashchenko, G. et al. (2012) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 17, 1187-95. PMID: 22961397

2. Baringer, SL. et al. (2023) Journal of biomedical science 30, 36. PMID: 37277838

Note

For research use only.

Images

Reférences

Fiche technique

Anti-HEPH Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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