

| Каталожный номер | HV304014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-HEPH Polyclonal Antibody (HV304014) is a rabbit polyclonal antibody detecting HEPH in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human HEPH (Ala24-Cys366). | ||||||||
| Цель | HEPH, KIAA0698, Hephaestin | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9BQS7 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Hephaestin is a ~130 kDa protein. Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. By helping iron transfer from cells to blood mainly contributes to dietary iron absorption by the intestinal epithelium and more generally regulates iron levels in the body. 1. Vashchenko, G. et al. (2012) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 17, 1187-95. PMID: 22961397 2. Baringer, SL. et al. (2023) Journal of biomedical science 30, 36. PMID: 37277838 | ||||||||
| Примечание | For research use only. |
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