

| Número de catálogo | HY126014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-HEXA Polyclonal Antibody (HY126014) is a rabbit polyclonal antibody detecting HEXA in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
|
||||||||
| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human HEXA (His318-Thr529). | ||||||||
| Objetivo | Beta-hexosaminidase subunit alpha, HEXA, Beta-N-acetylhexosaminidase subunit alpha, Hexosaminidase subunit A, N-acetyl-beta-glucosaminidase subunit alpha | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P06865 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
||||||||
| Información de uso del producto |
| ||||||||
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Beta-hexosaminidase subunit alpha (HEXA) is a ~60 kDa protein. Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. 1. Hepbildikler, ST. et al. (2002) The Journal of biological chemistry 277, 2562-72. PMID: 11707436 2. Novak, A. et al. (1994) Biochimica et biophysica acta 1199, 215-23. PMID: 8123671 3. Hou, Y. et al. (1996) Biochemistry 35, 3963-9. PMID: 8672428 4. Hou, Y. et al. (1998) The Journal of biological chemistry 273, 21386-92. PMID: 9694901 | ||||||||
| Nota | For research use only. |
Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]
Acceso rápido
Contáctenos
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский