Anti-HIC1 Polyclonal Antibody (HA798014)

Name: Anti-HIC1 Polyclonal Antibody
Brand: abinScience
SKU: HA798014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HA798014

説明

Anti-HIC1 Polyclonal Antibody (HA798014) is a rabbit polyclonal antibody detecting Hypermethylated in cancer 1 protein; Hic-1; Zinc finger and BTB domain-containing protein 29; HIC1; ZBTB29 in ELISA, IHC, WB. Suitable for Human, Mouse, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant human HIC1 (Lys561-Thr733).

ターゲット

Hypermethylated in cancer 1 protein; Hic-1; Zinc finger and BTB domain-containing protein 29; HIC1; ZBTB29

エンドトキシンレベル

Please contact with the lab for this information.

精製

Purified by antigen affinity column.

アクセッション番号

Q14526, Q9R1Y5, Q9JLZ6, Q90W33, Q96JB3

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Hypermethylated in cancer 1 protein (HIC1) is a ~76 kDa protein. Transcriptional repressor. Recognizes and binds to the consensus sequence '5-[CG]NG[CG]GGGCA[CA]CC-3'. May act as a tumor suppressor. Involved in development of head, face, limbs and ventral body wall. Involved in down-regulation of SIRT1 and thereby is involved in regulation of p53/TP53-dependent apoptotic DNA-damage responses.

1. Deltour, S. et al. (2002) Molecular and cellular biology 22, 4890-901. PMID: 12052894

2. Pinte, S. et al. (2004) The Journal of biological chemistry 279, 38313-24. PMID: 15231840

3. Zhang, W. et al. (2010) Oncogene 29, 2467-76. PMID: 20154726

4. Chen, WY. et al. (2005) Cell 123, 437-48. PMID: 16269335

5. Van Rechem, C. et al. (2010) Molecular and cellular biology 30, 4045-59. PMID: 20547755

6. Valenta, T. et al. (2006) The EMBO journal 25, 2326-37. PMID: 16724116

7. Briggs, KJ. et al. (2008) Genes & development 22, 770-85. PMID: 18347096

注意事項

For research use only

イメージ

参考文献

データシート

Anti-HIC1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-HIC1 Polyclonal Antibody (HA798014)

概要

イメージ

参考文献

データシート

SDS