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| カタログ番号 | HV758014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HIF2A/EPAS1 (Leu239-Asn350). | ||||||||
| ターゲット | Basic-helix-loop-helix-PAS protein MOP2, bHLHe73, HIF-2-alpha, Member of PAS protein 2, PAS domain-containing protein 2, HIF2A, HLF, EPAS1, Endothelial PAS domain-containing protein 1, EPAS-1, HIF-1-alpha-like factor, Hypoxia-inducible factor 2-alpha, MOP2, HIF2-alpha, BHLHE73, PASD2, Class E basic helix-loop-helix protein 73 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q99814 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Endothelial PAS domain-containing protein 1 (HIF2A/EPAS1) is a ~96 kDa protein. Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. | ||||||||
| 注意事項 | For research use only. |
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