

| Número de catálogo | VK497013 | ||||
|---|---|---|---|---|---|
| Descripción |
Anti-HIV-1 rev/ART/TRS protein Nanobody (SAA1422) [SAA1422] (VK497013) is a alpaca monoclonal antibody detecting ART/TRS in ELISA, IF.
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| Reactividad de especies | Human immunodeficiency virus type 1 (HIV-1) | ||||
| Aplicaciones | ELISA, IF | ||||
| Especie huésped | Alpaca | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | VHH-8His-Cys-tag | ||||
| ID de clon | SAA1422 | ||||
| Objetivo | Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins, rev | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Purified by Nickel column. | ||||
| Número de acceso | P04618 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Protein Rev (ART/TRS) is a ~13 kDa protein. Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs. Rev itself is translated from a fully spliced mRNA that readily exits the nucleus. Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1. | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-HIV-1 rev/ART/TRS protein Nanobody (SAA1422)
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