

| Numéro de catalogue | VK497013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-HIV-1 rev/ART/TRS protein Nanobody (SAA1422) [SAA1422] (VK497013) is a alpaca monoclonal antibody detecting ART/TRS in ELISA, IF.
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| Reactivité des espèces | Human immunodeficiency virus type 1 (HIV-1) | ||||
| Applications | ELISA, IF | ||||
| Espèce hôte | Alpaca | ||||
| Clonalité | Monoclonal | ||||
| Isotype | VHH-8His-Cys-tag | ||||
| ID de clone | SAA1422 | ||||
| Cible | Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins, rev | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by Nickel column. | ||||
| Numéro d'accès | P04618 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Protein Rev (ART/TRS) is a ~13 kDa protein. Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs. Rev itself is translated from a fully spliced mRNA that readily exits the nucleus. Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-HIV-1 rev/ART/TRS protein Nanobody (SAA1422)
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