

| Каталожный номер | VK497013 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-HIV-1 rev/ART/TRS protein Nanobody (SAA1422) [SAA1422] (VK497013) is a alpaca monoclonal antibody detecting ART/TRS in ELISA, IF.
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| Реактивность видов | Human immunodeficiency virus type 1 (HIV-1) | ||||
| Применения | ELISA, IF | ||||
| Хозяинский вид | Alpaca | ||||
| Клоональность | Monoclonal | ||||
| Изотип | VHH-8His-Cys-tag | ||||
| ID клона | SAA1422 | ||||
| Цель | Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins, rev | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Purified by Nickel column. | ||||
| Номер доступа | P04618 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Protein Rev (ART/TRS) is a ~13 kDa protein. Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs. Rev itself is translated from a fully spliced mRNA that readily exits the nucleus. Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1. | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-HIV-1 rev/ART/TRS protein Nanobody (SAA1422)
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