Anti-HIV-1 Vif/SOR protein Recombinant Nanobody (SAA1421) (VK454013)

Name: Anti-HIV-1 Vif/SOR protein Recombinant Nanobody (SAA1421)
Brand: abinScience
SKU: VK454013
Price: 191 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
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SDS

Обзор

Каталожный номер

VK454013

Описание

Anti-HIV-1 Vif/SOR protein Nanobody (SAA1421) [SAA1421] (VK454013) is a alpaca monoclonal antibody detecting SOR protein in ELISA, IP.

Реактивность видов

Human immunodeficiency virus type 1 (HIV-1)

Применения

ELISA, IP

Хозяинский вид

Alpaca

Клоональность

Monoclonal

Изотип

VHH-8His-Cys-tag

ID клона

SAA1421

Цель

Virion infectivity factor, Vif, SOR protein, p17, p7, vif

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Purified by Nickel column.

Номер доступа

P12504

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Virion infectivity factor (Vif/SOR protein) is a ~22 kDa protein. Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G by promoting their ubiquitination and degradation. Acts as a substrate recognition component of an E3 ubiquitin-protein ligase complex: mechanistically, Vif hijacks a host cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex) and the transcription coactivator CBFB/CBF-beta to form an active E3 ubiquitin-protein ligase complex that targets APOBEC3G and APOBEC3F for polyubiquitination, leading to their degradation by the proteasome. The complex can also ubiquitinate host APOBEC3H to some extent. Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism. May interact directly with APOBEC3G mRNA in order to inhibit its translation.

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-HIV-1 Vif/SOR protein Nanobody (SAA1421)

Ссылки

Даташит

Anti-HIV-1 Vif/SOR protein Recombinant Nanobody (SAA1421).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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