

| Número de catálogo | HC133014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-HKDC1 Polyclonal Antibody (HC133014) is a rabbit polyclonal antibody detecting HKDC1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human HKDC1 (Met1-Glu446). | ||||||||
| Objetivo | EC:2.7.1.1, HKDC1, Hexokinase HKDC1, Hexokinase domain-containing protein 1 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q2TB90, Q91W97 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Hexokinase HKDC1 is a ~102 kDa protein. Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases. Has low glucose phosphorylating activity compared to other hexokinases. Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role. 1. Pusec, CM. et al. (2019) Endocrinology 160, 313-330. PMID: 30517626 | ||||||||
| Nota | For research use only |
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