

| Numéro de catalogue | HC133014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-HKDC1 Polyclonal Antibody (HC133014) is a rabbit polyclonal antibody detecting HKDC1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human HKDC1 (Met1-Glu446). | ||||||||
| Cible | EC:2.7.1.1, HKDC1, Hexokinase HKDC1, Hexokinase domain-containing protein 1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q2TB90, Q91W97 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Hexokinase HKDC1 is a ~102 kDa protein. Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases. Has low glucose phosphorylating activity compared to other hexokinases. Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role. 1. Pusec, CM. et al. (2019) Endocrinology 160, 313-330. PMID: 30517626 | ||||||||
| Note | For research use only |
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