Anti-HMOX1 Polyclonal Antibody (HY063024)

Name: Anti-HMOX1 Polyclonal Antibody
Brand: abinScience
SKU: HY063024
Price: 96 USD
Availability: InStock

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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HY063024

Descripción

Anti-HMOX1 Polyclonal Antibody (HY063024) is a rabbit polyclonal antibody detecting HMOX1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human HMOX1 (Gln11-Ser229).

Objetivo

Heme oxygenase 1, HO-1, EC:1.14.14.18, Heme oxygenase 1 soluble form, HMOX1, HO, HO1

Nivel de endotoxinas

Please contact with the lab for this information.

Peso molecular observado

~30 kDa

Purificación

Purified by antigen affinity column.

Número de acceso

P09601, P14901

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Heme oxygenase 1 (HMOX1) is a ~32 kDa protein. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis.

1. Lightning, LK. et al. (2001) The Journal of biological chemistry 276, 10612-9. PMID: 11121422

2. Hwang, HW. et al. (2009) The Journal of biological chemistry 284, 22672-9. PMID: 19556236

3. Wilks, A. et al. (1995) Biochemistry 34, 4421-7. PMID: 7703255

4. Gozzelino, R. et al. (2010) Annual review of pharmacology and toxicology 50, 323-54. PMID: 20055707

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-HMOX1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo