Anti-HMOX1 Polyclonal Antibody (HY063024)

Name: Anti-HMOX1 Polyclonal Antibody
Brand: abinScience
SKU: HY063024
Price: 96 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HY063024

Description

Anti-HMOX1 Polyclonal Antibody (HY063024) is a rabbit polyclonal antibody detecting HMOX1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human HMOX1 (Gln11-Ser229).

Cible

Heme oxygenase 1, HO-1, EC:1.14.14.18, Heme oxygenase 1 soluble form, HMOX1, HO, HO1

Niveau d'endotoxines

Please contact with the lab for this information.

Masse moléculaire observée

~30 kDa

Purification

Purified by antigen affinity column.

Numéro d'accès

P09601, P14901

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Heme oxygenase 1 (HMOX1) is a ~32 kDa protein. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis.

1. Lightning, LK. et al. (2001) The Journal of biological chemistry 276, 10612-9. PMID: 11121422

2. Hwang, HW. et al. (2009) The Journal of biological chemistry 284, 22672-9. PMID: 19556236

3. Wilks, A. et al. (1995) Biochemistry 34, 4421-7. PMID: 7703255

4. Gozzelino, R. et al. (2010) Annual review of pharmacology and toxicology 50, 323-54. PMID: 20055707

Note

For research use only

Images

Reférences

Fiche technique

Anti-HMOX1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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