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| カタログ番号 | VK739014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human metapneumovirus (HMPV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant HMPV Phosphoprotein/P (Met1-Met294). | ||||||||
| ターゲット | Phosphoprotein, Protein P, P | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8B9Q8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Phosphoprotein is a ~32 kDa protein. Plays critical roles in regulating RNA replication and transcription through its interactions with multiple proteins. Tethers the RNA-directed RNA polymerase L to the nucleoprotein-RNA complex. Recruits the M2-1 protein, a processivity factor that is required for efficient transcription of viral RNA. Acts as a chaperone for neo-synthesized nucleoprotein by forming an N-P complex that preserves N in a monomeric and RNA-free state and prevents the association of nascent N with host cell RNAs. Recruits the host phosphatase PP1 to inclusion bodies to regulate viral transcription. 1. Pan, J. et al. (2020) Nature 577, 275-279. PMID: 31698413 | ||||||||
| 注意事項 | For research use only. |
Lane 1: recombinant HMPV Phosphoprotein/P (Catalog No: VK739012)
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中国武漢市深敦寺路666号C棟、武漢、430206
