

| Número de catálogo | VK530014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human metapneumovirus (HMPV) | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant HMPV SH/Small hydrophobic protein (Asn51-Asp179). | ||||||||
| Objetivo | Small hydrophobic protein, SH | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q6WB95 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Small hydrophobic protein (SH) is a ~20 kDa protein. Viroporin that forms a ion channel probably displaying low ion selectivity. Plays a role in counteracting host innate immunity by inhibiting TLR7/MyD88/TRAF6 signaling and STAT1 phosphorylation, leading to down-regulation of type-I IFN. 1. Masante, C. et al. (2014) Journal of virology 88, 6423-33. PMID: 24672047 2. Hastings, AK. et al. (2016) Virology 494, 248-56. PMID: 27131212 3. Bao, X. et al. (2018) Viruses 10. PMID: 29789500 | ||||||||
| Nota | For research use only. |
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