Anti-HPeV-1 VP3 Polyclonal Antibody (VK085024) is a rabbit polyclonal antibody detecting Capsid protein VP3 in ELISA, IHC, WB.
Highlights
●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
Реактивность видов
Human parechovirus 1 (HPeV-1)
Применения
ELISA, IHC, WB
Хозяинский вид
Rabbit
Клоональность
Polyclonal
Изотип
IgG
Иммуноген
E. coli - derived recombinant HPeV-1 Genome polyprotein (Leu361-Gln542).
Цель
Genome polyprotein, Capsid protein VP0, P1AB, Virion protein 0, Capsid protein VP3, P1C, Virion protein 3, Capsid protein VP1, P1D, Virion protein 1, Protein 2A H-NC, P2A, Protein 2A, Protein 2B, P2B, Protein 2C, P2C, 3.6.1.15, Protein 3A, P3A, Viral protein genome-linked, VPg, Protein 3B, P3B, Protease 3C, P3C, 3.4.22.28, Picornain 3C, RNA-directed RNA polymerase 3D-POL, P3D-POL, 2.7.7.48
Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Информация об использовании продукта
Применение
Разбавление
ELISA
1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000
Устойчивость и хранение
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон
Genome polyprotein (VP3) is a ~245 kDa protein. Forms an icosahedral capsid of pseudo T=3 symmetry together with capsid proteins VP1 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid proteins interact with host alpha-V/beta-3 integrin heterodimer to provide virion attachment target cell. This attachment induces virion internalization predominantly through clathrin-mediated endocytosis. Binds packaging signals present in the viral RNA.
1. Joki-Korpela, P. et al. (2001) Journal of virology 75, 1958-67. PMID: 11160695
2. Shakeel, S. et al. (2017) Nature communications 8, 5. PMID: 28232749
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