

| Numéro de catalogue | HT490014 | ||||||||
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| Description |
Anti-HPGDS Polyclonal Antibody (HT490014) is a rabbit polyclonal antibody detecting HPGDS in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human HPGDS (Met1-Leu199). | ||||||||
| Cible | GST class-sigma, Prostaglandin-H2 D-isomerase, PTGDS2, Glutathione-dependent PGD synthase, Hematopoietic prostaglandin D synthase, PGDS, HPGDS, Glutathione-requiring prostaglandin D synthase, GSTS, H-PGDS, Glutathione S-transferase | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O60760 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Hematopoietic prostaglandin D synthase (HPGDS) is a ~23 kDa protein. Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. | ||||||||
| Reférences | 1. Niitsu Y, et al. Implications of glutathione-S transferase P1 in MAPK signaling as a CRAF chaperone: In memory of Dr. Irving Listowsky. Proc Jpn Acad Ser B Phys Biol Sci. 2022;98(2):72-86. [HT490014] | ||||||||
| Note | For research use only. |
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