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| カタログ番号 | HT490014 | ||||||||
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| 説明 |
Anti-HPGDS Polyclonal Antibody (HT490014) is a rabbit polyclonal antibody detecting HPGDS in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HPGDS (Met1-Leu199). | ||||||||
| ターゲット | GST class-sigma, Prostaglandin-H2 D-isomerase, PTGDS2, Glutathione-dependent PGD synthase, Hematopoietic prostaglandin D synthase, PGDS, HPGDS, Glutathione-requiring prostaglandin D synthase, GSTS, H-PGDS, Glutathione S-transferase | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O60760 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Hematopoietic prostaglandin D synthase (HPGDS) is a ~23 kDa protein. Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. | ||||||||
| 参考文献 | 1. Niitsu Y, et al. Implications of glutathione-S transferase P1 in MAPK signaling as a CRAF chaperone: In memory of Dr. Irving Listowsky. Proc Jpn Acad Ser B Phys Biol Sci. 2022;98(2):72-86. [HT490014] | ||||||||
| 注意事項 | For research use only. |
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