

| Каталожный номер | VK451013 | ||||||
|---|---|---|---|---|---|---|---|
| Реактивность видов | Human papillomavirus 16 (HPV16) | ||||||
| Применения | ELISA, Neutralization, WB | ||||||
| Хозяинский вид | Mouse | ||||||
| Клоональность | Monoclonal | ||||||
| Изотип | VHH-mFC | ||||||
| ID клона | Nb9 | ||||||
| Цель | E6, Protein E6 | ||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||
| Чистота | >95% as determined by SDS-PAGE. | ||||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||||
| Номер доступа | P03126 | ||||||
| RRID | Anti-HPV16 E6/Protein E6 Antibody (Nb9) (abinScience Cat# VK451013, RRID:AB_3725278) |
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| Форма | Liquid | ||||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Фон | Protein E6 is a ~19 kDa protein. Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). | ||||||
| Примечание | For research use only. |

SDS-PAGE for Anti-HPV16 E6/Protein E6 Antibody (Nb9)




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