Anti-HPV18 E7/Protein E7 Recombinant Antibody (SAA2229) (VK556063)

Name: Anti-HPV18 E7/Protein E7 Recombinant Antibody (SAA2229)
Brand: abinScience
SKU: VK556063
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK556063

Reactividad de especies

Human papillomavirus 16 (HPV16), Human papillomavirus 18 (HPV18)

Aplicaciones

ELISA, IP, WB, ICC, IHC

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA2229

Sistema de expresión

Mammalian cells

Objetivo

Nivel de endotoxinas

<10 EU/mg

Pureza

>95% purity as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P06788

RRID

Anti-HPV18 E7/Protein E7 Antibody (SAA2229) (abinScience Cat# VK556063, RRID:AB_3729825)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Nombres alternativos

Protein E7, E7

Fondo

Protein E7 is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.

1. Lau, L. et al. (2015) Science (New York, N.Y.) 350, 568-71. PMID: 26405230

Nota

For research use only.

Imágenes