

| Número de catálogo | VK556054 | ||||
|---|---|---|---|---|---|
| Descripción |
Anti-HPV31 E7 Polyclonal Antibody (VK556054) is a rabbit polyclonal antibody detecting Protein E7 in ELISA, IHC, WB.
Highlights
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| Reactividad de especies | Human papillomavirus 31 (HPV31) | ||||
| Aplicaciones | ELISA, IHC, WB | ||||
| Especie huésped | Rabbit | ||||
| Clonalidad | Polyclonal | ||||
| Isotipo | IgG | ||||
| Inmunógeno | E. coli - derived recombinant HPV31 E7 (Met1-Leu98). | ||||
| Objetivo | Protein E7, E7 | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Purificación | Purified by antigen affinity column. | ||||
| Número de acceso | P17387 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Protein E7 is a ~10 kDa protein. E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. | ||||
| Nota | For research use only |




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