

| Каталожный номер | VK556054 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-HPV31 E7 Polyclonal Antibody (VK556054) is a rabbit polyclonal antibody detecting Protein E7 in ELISA, IHC, WB.
Highlights
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| Реактивность видов | Human papillomavirus 31 (HPV31) | ||||
| Применения | ELISA, IHC, WB | ||||
| Хозяинский вид | Rabbit | ||||
| Клоональность | Polyclonal | ||||
| Изотип | IgG | ||||
| Иммуноген | E. coli - derived recombinant HPV31 E7 (Met1-Leu98). | ||||
| Цель | Protein E7, E7 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Очистка | Purified by antigen affinity column. | ||||
| Номер доступа | P17387 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Protein E7 is a ~10 kDa protein. E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. | ||||
| Примечание | For research use only |




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