

| Número de catálogo | VK556143 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Human papillomavirus 31 (HPV31) | ||||
| Aplicaciones | ELISA, IHC | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a, kappa | ||||
| ID de clon | SAA2461 | ||||
| Sistema de expresión | Mammalian cells | ||||
| Nivel de endotoxinas | <10 EU/mg | ||||
| Pureza | >95% purity as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | P17387 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. | ||||
| Nombres alternativos | Protein E7, E7 | ||||
| Fondo | Protein E7 is a ~10 kDa protein. E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-HPV31 E7/Protein E7 Antibody (SAA2461)




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