

| Número de catálogo | VK424014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-HPV52 E7/Protein E7 Polyclonal Antibody (VK424014) is a rabbit polyclonal antibody detecting Protein E7 in ELISA, IHC, WB.
Highlights
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| Reactividad de especies | Human papillomavirus 52 (HPV52) | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant HPV52 E7/Protein E7 (Arg2-Leu99). | ||||||||
| Objetivo | Protein E7, E7 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P36831 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Protein E7 is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-HPV-E7 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant HPV52 E7/Protein E7 (Catalog No: VK424022)




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