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| カタログ番号 | VK424044 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-HPV58 E7 Polyclonal Antibody (VK424044) is a rabbit polyclonal antibody detecting HPV58 E7 in ELISA, IHC, WB.
Highlights
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| 種反応性 | Human papillomavirus 58 (HPV58) | ||||
| アプリケーション | ELISA, IHC, WB | ||||
| 宿主種 | Rabbit | ||||
| クローン性 | Polyclonal | ||||
| アイソタイプ | IgG | ||||
| 免疫原 | E. coli - derived recombinant HPV58 E7 (Arg2-Gln98). | ||||
| ターゲット | unnamed protein product, unnamed protein product | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 精製 | Purified by antigen affinity column. | ||||
| アクセッション番号 | P26557 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Protein E7 is a ~10 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. | ||||
| 注意事項 | For research use only |
Western blot analysis was performed using anti-E7-HPV58 polyclonal antibody at 1ug/mL on various samples.
Lane 1: ATG18887 100ng
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