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| カタログ番号 | HB704014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-HSP40/DNAJB1 Polyclonal Antibody (HB704014) is a rabbit polyclonal antibody detecting DNAJB1 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HSP40/DNAJB1 (Met1-Ile340). | ||||||||
| ターゲット | DnaJ protein homolog 1, HSP40, DnaJ homolog subfamily B member 1, DNAJB1, DNAJ1, Heat shock 40 kDa protein 1, hDj-1, HDJ1, Human DnaJ protein 1, Heat shock protein 40, HSPF1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P25685 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | DnaJ homolog subfamily B member 1 (HSP40/DNAJB1) is a ~38 kDa protein. Interacts with HSP70 and can stimulate its ATPase activity. Acts also with TTC1 as a chaperone adapter that regulates HSP70-dependent folding process by interacting with the HSP70 amino terminal region. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). 1. Oh, WK. et al. (2003) Molecules and cells 16, 84-91. PMID: 14503850 2. Shi, Y. et al. (1998) Genes & development 12, 654-66. PMID: 9499401 3. Rauch, JN. et al. (2014) The Journal of biological chemistry 289, 1402-14. PMID: 24318877 | ||||||||
| 注意事項 | For research use only. |
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