Anti-HSPA1L Polyclonal Antibody (HW649014)

Name: Anti-HSPA1L Polyclonal Antibody
Brand: abinScience
SKU: HW649014
Price: 96 USD
Availability: InStock

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SDS

Vista general

Número de catálogo

HW649014

Descripción

Anti-HSPA1L Polyclonal Antibody (HW649014) is a rabbit polyclonal antibody detecting HSPA1L in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Bos mutus grunniens.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human HSPA1L (Met1-Asp641).

Objetivo

HSP70-Hom, Heat shock 70 kDa protein 1L, Heat shock 70 kDa protein 1-like, HSPA1L, Heat shock 70 kDa protein 1-Hom

Purificación

Purified by antigen affinity column.

Número de acceso

P34931

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Heat shock 70 kDa protein 1-like (HSPA1L) is a ~70 kDa protein. Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins.

1. Radons, J. (2016) Cell stress & chaperones 21, 379-404. PMID: 26865365

2. Hasson, SA. et al. (2013) Nature 504, 291-5. PMID: 24270810

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-HSPA1L polyclonal antibody at 1μg/ml on various samples.
Lane 1: PC12 cell lysate
Lane 2: HepG2 cell lysate
Lane 3: Human plasma lysate
Lane 4: Mouse spleen lysate
Lane 5: Mouse liver lysate
Lane 6: Mouse kidney lysate
Lane 7: Mouse lung lysate
Lane 8: Rat spleen lysate
Lane 9: Rat liver lysate
Lane 10: Rat kidney lysate

Referencias

Datasheet

Anti-HSPA1L Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-HSPA1L Polyclonal Antibody (HW649014)

Vista general

Imágenes

Referencias

Datasheet

SDS