

| カタログ番号 | HY322014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-HSPB1/HSP27 Polyclonal Antibody (HY322014) is a rabbit polyclonal antibody detecting HspB1 in ELISA, IHC, WB. Suitable for Human and Pig.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HSPB1/HSP27 (Met1-Lys205). | ||||||||
| ターゲット | Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, SRP27, Heat shock protein beta-1, Stress-responsive protein 27, HspB1, 28 kDa heat shock protein, HSPB1, HSP27, HSP28, HSP 27 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P04792 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Heat shock protein beta-1 (HSPB1/HSP27) is a ~22 kDa protein. Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. 1. Rogalla, T. et al. (1999) The Journal of biological chemistry 274, 18947-56. PMID: 10383393 2. Almeida-Souza, L. et al. (2010) The Journal of biological chemistry 285, 12778-86. PMID: 20178975 3. Kostenko, S. et al. (2009) Cellular signalling 21, 712-8. PMID: 19166925 4. Holmgren, A. et al. (2013) Acta neuropathologica 126, 93-108. PMID: 23728742 | ||||||||
| 注意事項 | For research use only. |
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