

| Numéro de catalogue | VK746014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-HSV-1/HHV-1 gE Polyclonal Antibody (VK746014) is a rabbit polyclonal antibody detecting HSV-1/HHV-1 gE in ELISA, IHC, WB.
Highlights
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| Reactivité des espèces | Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant HSV-1/HHV-1 gE (Lys24-Arg419). | ||||||||
| Cible | gE, Envelope glycoprotein E | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P04488 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Envelope glycoprotein E (gE) is a ~59 kDa protein. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips. | ||||||||
| Note | For research use only. |




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