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| カタログ番号 | VK746014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-HSV-1/HHV-1 gE Polyclonal Antibody (VK746014) is a rabbit polyclonal antibody detecting HSV-1/HHV-1 gE in ELISA, IHC, WB.
Highlights
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| 種反応性 | Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant HSV-1/HHV-1 gE (Lys24-Arg419). | ||||||||
| ターゲット | gE, Envelope glycoprotein E | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P04488 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Envelope glycoprotein E (gE) is a ~59 kDa protein. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips. | ||||||||
| 注意事項 | For research use only. |
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