

| Numéro de catalogue | VK006033 | ||||
|---|---|---|---|---|---|
| Description |
Anti-HSV Glycoprotein B/gB Nanobody (SAA2381) [SAA2381] (VK006033) is a alpaca monoclonal antibody detecting HSV Glycoprotein B/gB in ELISA, Neutralization. Suitable for HSV-1 and HSV-2.
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| Reactivité des espèces | Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1), Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2) | ||||
| Applications | ELISA, Neutralization | ||||
| Espèce hôte | Alpaca | ||||
| Clonalité | Monoclonal | ||||
| Isotype | VHH-His | ||||
| ID de clone | SAA2381 | ||||
| Cible | Envelope glycoprotein B, gB, gB | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | P06437 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Envelope glycoprotein B (gB) is a ~100 kDa protein. Envelope glycoprotein that forms spikes at the surface of virion envelope and binds to the host cell entry receptors MYH9/NMMHC-IIA and MYH10/NMMHC-IIB, promoting the virus entry into host cells. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell: following initial binding to its host cell entry receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress. Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation). | ||||
| Note | For research use only |

SDS-PAGE for Anti-HSV Glycoprotein B/gB Nanobody (SAA2381)
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