Anti-Mouse HTR1A Polyclonal Antibody (MY581014)

Name: Anti-Mouse HTR1A Polyclonal Antibody
Brand: abinScience
SKU: MY581014
Price: 168 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) : --

Spécification :

50ug
100ug

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MY581014

Description

Anti-HTR1A Polyclonal Antibody (MY581014) is a rabbit polyclonal antibody detecting 5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; Serotonin receptor 1A; Htr1a; Gpcr18 in ELISA, IHC, WB. Suitable for Mouse and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant mouse HTR1A (Ile218-Lys345).

Cible

5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; Serotonin receptor 1A; Htr1a; Gpcr18

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q64264, P19327

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

5-hydroxytryptamine receptor 1A (HTR1A) is a ~46 kDa protein. G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1A is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission: signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Beta-arrestin family members regulate signaling by mediating both receptor desensitization and resensitization processes.

1. Ase, AR. et al. (2000) Journal of neurochemistry 75, 2415-26. PMID: 11080193

2. Deng, DR. et al. (2007) Neuroscience 147, 388-402. PMID: 17543467

3. Audero, E. et al. (2008) Science (New York, N.Y.) 321, 130-3. PMID: 18599790

4. Richardson-Jones, JW. et al. (2011) The Journal of neuroscience : the official journal of the Society for Neuroscience 31, 6008-18. PMID: 21508226

5. Charest, A. et al. (1993) The Journal of neuroscience : the official journal of the Society for Neuroscience 13, 5164-71. PMID: 8254366

6. Ramboz, S. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 14476-81. PMID: 9826725

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Mouse HTR1A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Mouse HTR1A Polyclonal Antibody (MY581014)

Aperçu

Images

Reférences

Fiche technique

SDS