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Anti-Human ABRAXAS1 Polyclonal Antibody (HD497014)

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Vista general
Número de catálogoHD497014
Descripción
Anti-Human ABRAXAS1 Polyclonal Antibody (HD497014) is a rabbit polyclonal antibody detecting ABRAXAS1. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human ABRAXAS1 (Met1-Ser174).
Objetivo ABRA1, ABRAXAS1, BRCA1-A complex subunit Abraxas 1, CCDC98, Coiled-coil domain-containing protein 98, FAM175A, Protein FAM175A
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q6UWZ7
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

BRCA1-A complex subunit Abraxas 1 (ABRAXAS1) is a ~46 kDa protein. Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

Nota For research use only
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Formula
C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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C₂ (Working Conc.)
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