Anti-Human ACTR2 Polyclonal Antibody (HX063014)

Name: Anti-Human ACTR2 Polyclonal Antibody
Brand: abinScience
SKU: HX063014
Price: 168 USD
Availability: InStock

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HX063014

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human ACTR2 (Met1-Arg394).

Цель

Actin-like protein 2, ARP2, Actin-related protein 2, ACTR2

Очистка

Purified by antigen affinity column.

Номер доступа

P61160

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Actin-related protein 2 (ACTR2) is a ~44 kDa protein. ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.

1. Welch, MD. et al. (1997) Nature 385, 265-9. PMID: 9000076

2. Rao, J. et al. (2017) The Journal of clinical investigation 127, 4257-4269. PMID: 29058690

3. Yoo, Y. et al. (2007) The Journal of biological chemistry 282, 7616-23. PMID: 17220302

4. Schrank, BR. et al. (2018) Nature 559, 61-66. PMID: 29925947

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human ACTR2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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