Anti-Human ADAMTS4 Recombinant Antibody (4D8) (HF893013)

Name: Anti-Human ADAMTS4 Recombinant Antibody (4D8)
Brand: abinScience
SKU: HF893013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF893013

Reactividad de especies

Human

Aplicaciones

ELISA, Neutralization

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG1

ID de clon

4D8

Objetivo

ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, ADAMTS-4, ADMP-1, Aggrecanase-1

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Productos asociados

pH 7.4 Dilution Buffer

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

O75173

RRID

Anti-Human ADAMTS4 Antibody (4D8) (abinScience Cat# HF893013, RRID:AB_3725377)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4) is a ~90 kDa protein. Cleaves aggrecan, a cartilage proteoglycan, at the '392-Glu-|-Ala-393' site and may be involved in its turnover. Also cleaves COMP. May play an important role in the destruction of aggrecan in arthritic diseases. Could be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease.

1. Tortorella, MD. et al. (1999) Science (New York, N.Y.) 284, 1664-6. PMID: 10356395

2. Tortorella, M. et al. (2000) The Journal of biological chemistry 275, 25791-7. PMID: 10827174

3. de Groot, R. et al. (2025) Matrix biology : journal of the International Society for Matrix Biology 135, 106-124. PMID: 39672391

Nota

For research use only.

Imágenes