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| カタログ番号 | HA124013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1866 | ||||
| ターゲット | Adhesion G-protein coupled receptor G2, HE6, TM7LN2, Human epididymis-specific protein 6, ADGRG2, He6, G-protein coupled receptor 64, GPR64 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q8IZP9 | ||||
| RRID | Anti-Human ADGRG2/GPR64 Antibody (SAA1866) (abinScience Cat# HA124013, RRID:AB_3727629) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Adhesion G-protein coupled receptor G2 (ADGRG2/GPR64) is a ~111 kDa protein. Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as dehydroepiandrosterone (DHEA; also named 3beta-hydroxyandrost-5-en-17-one) and androstenedione. Involved in a signal transduction pathway controlling epididymal function and male fertility. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG2 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Also able to couple with G(q) G proteins in vitro. 1. Zhang, DL. et al. (2018) eLife 7. PMID: 29393851 2. Lin, H. et al. (2022) Nature chemical biology 18, 1196-1203. PMID: 35982227 3. Yang, Z. et al. (2025) Cell 188, 1589-1604.e24. PMID: 39884271 4. Sun, Y. et al. (2021) The Journal of biological chemistry 296, 100174. PMID: 33303626 5. Gad, AA. et al. (2021) Scientific reports 11, 14060. PMID: 34234254 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human ADGRG2/GPR64 Antibody (SAA1866)
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