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Anti-Human ADRB1 Recombinant Antibody (6B9) (HY486107)

Anti-Human ADRB1 Recombinant Antibody (6B9)
Anti-Human ADRB1 Recombinant Antibody (6B9)
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Especificación:
  • 50ug
  • 100ug
Número:
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  • Datasheet

  • SDS

Vista general
Número de catálogoHY486107
Reactividad de especiesHuman
AplicacionesELISA, FCM
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoVHH-hFc
ID de clon6B9
Objetivo Beta-1 adrenoreceptor, ADRB1, Beta-1 adrenergic receptor, ADRB1R, B1AR, Beta-1 adrenoceptor
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P08588
Forma Liquid
Buffer de almacenamiento 9mM Citric acid monohydrate, 41mM Na2HPO4, 1% Mannitol, 5% Trehalose, 0.02% Tween 20, pH 6.5.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Beta-1 adrenergic receptor (ADRB1) is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes.

1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248
2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161
3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775
4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660
5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857
6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867
7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062
Nota For research use only.
Imágenes
  • Anti-Human ADRB1 Recombinant Antibody (6B9)

    SDS-PAGE

    SDS-PAGE for Anti-Human ADRB1 Antibody (6B9)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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