Anti-Human ADRB1 Recombinant Antibody (6B9) (HY486107)

Name: Anti-Human ADRB1 Recombinant Antibody (6B9)
Brand: abinScience
SKU: HY486107
Price: 191 USD
Availability: InStock

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概要
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概要

カタログ番号	HY486107
種反応性	Human
アプリケーション	ELISA, FCM
宿主種	Human
クローン性	Monoclonal
アイソタイプ	VHH-hFc
クローンID	6B9
ターゲット	Beta-1 adrenoreceptor, ADRB1, Beta-1 adrenergic receptor, ADRB1R, B1AR, Beta-1 adrenoceptor
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P08588
形態	Liquid
保存バッファー	9mM Citric acid monohydrate, 41mM Na2HPO4, 1% Mannitol, 5% Trehalose, 0.02% Tween 20, pH 6.5. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Beta-1 adrenergic receptor (ADRB1) is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes. 1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248 2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775 4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660 5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857 6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867 7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062
注意事項	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human ADRB1 Antibody (6B9)

参考文献

データシート

Anti-Human ADRB1 Recombinant Antibody (6B9).pdf

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Formula

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Anti-Human ADRB1 Recombinant Antibody (6B9) (HY486107)

概要

イメージ

参考文献

データシート

SDS

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